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Successes and failures of conservation actions to halt global river biodiversity loss
To address the losses of river biodiversity worldwide, various conservation actions have been implemented to promote recovery of species and ecosystems. In this Review, we assess the effectiveness of these actions globally and regionally, and identify causes of success and failure. Overall, actions elicit little improvement in river biodiversity, in contrast with reports from terrestrial and marine ecosystems. This lack of improvement does not necessarily indicate a failure of any individual action. Rather, it can be attributed in part to remaining unaddressed stressors driving biodiversity loss; a poor match between the spatial scale of action and the scale of the affected area; and absence of adequate monitoring, including insufficient timescales, missing reference and control sites or insufficient selection of targeted taxa. Furthermore, outcomes are often not reported and are unevenly distributed among actions, regions and organism groups. Expanding from local-scale actions to coordinated, transformative, catchment-scale management approaches shows promise for improving outcomes. Such approaches involve identifying major stressors, appropriate conservation actions and source populations for recolonization, as well as comprehensive monitoring, relevant legislation and engaging all stakeholders to promote the recovery of river biodiversity.
The role of rivers in the origin and future of Amazonian biodiversity
The rich biodiversity of Amazonia is shaped geographically and ecologically by its rivers and their cycles of seasonal flooding. Anthropogenic effects, such as deforestation, infrastructure development and extreme climatic events, threaten the ecological processes sustaining Amazonian ecosystems. In this Review, we explore the coupled evolution of Amazonian rivers and biodiversity associated with terrestrial and seasonally flooded environments, integrating geological, climatic, ecological and genetic evidence. Amazonia and its fluvial environments are highly heterogeneous, and the drainage system is historically dynamic and continually evolving; as a result, the discharge, sediment load and strength of rivers as barriers to biotic dispersal has changed through time. Ecological affinities of taxa, drainage rearrangements and variations in riverine landscape caused by past climate changes have mediated the evolution of the high diversity found in modern-day Amazonia. The connected history of the region’s biodiversity and landscape provides fundamental information for mitigating current and future impacts. However, incomplete knowledge about species taxonomy, distributions, habitat use, ecological interactions and occurrence patterns limits our understanding. Partnerships with Indigenous peoples and local communities, who have close ties to land and natural resources, are key to improving knowledge generation and dissemination, enabling better impact assessments, monitoring and management of the riverine systems at risk from evolving pressures.
Sustainable supply chain management practices and performance: The moderating effect of stakeholder pressure
Currently, sustainable supply chain management practices have become an important strategy for firms to improve performance and gain competitive advantage. However, there is a current debate over the performance outcomes of sustainable supply chain management practices. Additionally, the role of stakeholder pressure is frequently overlooked. Drawing on Natural Resources-Based View and Stakeholder Theory, this study aims to elucidate the ambiguous connection between sustainable supply management, sustainable process management, stakeholder pressure and performance, and investigate the mediation role of sustainable process management and the moderation effect of stakeholder pressure. Our analysis, based on data collected from 235 Chinese manufacturing firms, reveals significant insights. First, stakeholder pressure positively moderates the relationship between sustainable process management and performance, while negatively moderates the relationship between sustainable supply management and performance. Second, sustainable process management has a complete mediation effect on the relationship between sustainable supply management and performance. The conclusion not only explains the inconsistent relationship between sustainable supply chain management practice and performance, but also reveals clearly the relationship between sustainable supply management and sustainable process management. Besides, it also highlights the difference in performance outcomes of sustainable supply management and sustainable process management under stakeholder pressures, and has valuable guidance to the practice of sustainable supply chain management in Chinese manufacturing firms.
Type 2 immunity in allergic diseases
Significant advancements have been made in understanding the cellular and molecular mechanisms of type 2 immunity in allergic diseases such as asthma, allergic rhinitis, chronic rhinosinusitis, eosinophilic esophagitis (EoE), food and drug allergies, and atopic dermatitis (AD). Type 2 immunity has evolved to protect against parasitic diseases and toxins, plays a role in the expulsion of parasites and larvae from inner tissues to the lumen and outside the body, maintains microbe-rich skin and mucosal epithelial barriers and counterbalances the type 1 immune response and its destructive effects. During the development of a type 2 immune response, an innate immune response initiates starting from epithelial cells and innate lymphoid cells (ILCs), including dendritic cells and macrophages, and translates to adaptive T and B-cell immunity, particularly IgE antibody production. Eosinophils, mast cells and basophils have effects on effector functions. Cytokines from ILC2s and CD4+ helper type 2 (Th2) cells, CD8 + T cells, and NK-T cells, along with myeloid cells, including IL-4, IL-5, IL-9, and IL-13, initiate and sustain allergic inflammation via T cell cells, eosinophils, and ILC2s; promote IgE class switching; and open the epithelial barrier. Epithelial cell activation, alarmin release and barrier dysfunction are key in the development of not only allergic diseases but also many other systemic diseases. Recent biologics targeting the pathways and effector functions of IL4/IL13, IL-5, and IgE have shown promising results for almost all ages, although some patients with severe allergic diseases do not respond to these therapies, highlighting the unmet need for a more detailed and personalized approach.
Management practices and manufacturing firm responses to a randomized energy audit
Increasing the efficiency of industrial energy use is widely considered important for mitigating climate change. We randomize assignment of an energy audit intervention aimed at improving energy efficiency and reducing energy expenditures of small- and medium-sized metal processing firms in Shandong Province, China, and examine impacts on energy outcomes and interactions with firms’ management practices. We find that the intervention reduced firms’ unit cost of electricity by 8% on average. Firms with more developed structured management practices showed higher rates of recommendation adoption. However, the post-intervention electricity unit cost reduction is larger in firms with less developed practices, primarily driven by a single recommendation that corrected managers’ inaccurate reporting of transformer usage at baseline, lowering their electricity costs. By closing management-associated gaps in awareness of energy expenditures, energy audit programmes may reduce a firm’s unit cost of energy but have an ambiguous impact on energy use and climate change.
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